A research team has discovered a novel mechanism essential for initiating autophagy. The study highlights the role of ZDHHC13, an enzyme that palmitoylates ULK1, in triggering autophagy. This ...

An international research team led by Osaka University has identified a new mechanism crucial for the initiation of autophagy, a self-degradation process cells use to eliminate unneeded or damaged ...

Tsukuba, Japan—In Japan, cancer has been the leading cause of death since 1981. At present, surgery, chemotherapy, and radiotherapy are the main treatment options. However, these treatments ...

Researchers at the Max Delbrück Center have found that a cellular housekeeping mechanism called autophagy plays a major role ...

New findings could aid future development of more efficient therapeutic strategies in the context of regenerative medicine and aging.

A new study unravels the relationship between mitofusins (mitochondrial proteins) and autophagy. Using gene editing with CRISPR-Cas9, the team has been able to study these proteins without altering ...

Autophagy, derived from a Greek word, the "self-eating" nature refers to an interesting cellular process as part of the body's own recycling mechanism for cellular damage or components that have no ...

Four genetic variants associated with autophagy are linked to increased CLL risk, providing insights into disease biology and potential future screening efforts. The study confirmed associations ...