A closeup look at colibactin’s structure reveals chemical motifs that guide its mutation-wreaking “warheads” to specific stretches of DNA.

Colibactin is a powerful toxin produced by Escherichia coli and other bacteria living in the human gut. This highly unstable ...

DNA itself is made from four chemical building blocks, or bases, which are strung together in endlessly varied combinations. It's the order of these bases -- adenine (A), thymine (T), guanine (G) and ...

Fresh from solving the protein structure challenge, Google’s deep-learning outfit is moving on to the human genome. Google DeepMind says it’s trained an artificial intelligence that can predict which ...

A study conducted by the Development and Growth Control Laboratory at IRB Barcelona sheds light on the contribution of DNA damage to the invasiveness of cancer cells. The discovery challenges the ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

A major new discovery may help scientists figure what causes autism, which is diagnosed in one of every 150 children, doctors say. The answer might come from looking deep within the human genome, said ...

After a 25-year-long search, a new sequencing technique has helped researchers pinpoint the genetic cause of SCA4, a rare movement disorder. Spinocerebellar ataxia 4 (SCA4) is a rare genetic condition ...

The oldest known plague victims date back to around 5,000 years ago in Europe. But it’s never been clear whether two cases, one in Latvia and one in Sweden, were isolated and sporadic or evidence of a ...