Background Lactate dehydrogenase (LDH) isoenzymes are required for adenosine triphosphate production, with each of five different isoenzymes having varying proficiencies in anaerobic versus aerobic ...

Higher lactate concentrations and hypotension are independently linked to increased mortality risk in critically ill adults with COVID-19.

For a long time, muscular fatigue during exercise was believed to be caused primarily by lactate as a by-product of glycolysis (glucose metabolism). In early studies, lactate was shown to increase in ...

In clinical practice, lactate is a well-established tool for establishing diagnosis and prognosis in critically ill patients. 1 It can be used to diagnose sepsis and can also help in monitoring ...

A new study on fulminant hepatic failure (FHF), a sudden and severe shutdown of the liver, examined ways of determining early on whether patients would benefit from a transplant as opposed to ...

Some past studies have shown that the biomarkers PD-1 and PD-L1 are associated with response to ICI treatment in NSCLC as well as PFS and OS. Authors of past studies have also suggested that ...

A meta-analysis of two randomized, double-blind, placebo-controlled, phase III studies in patients (pts) with metastatic colorectal cancer (mCRC) receiving FOLFOX4 and PTK/ZK to determine clinical ...

Dynamic angiogenic switch as predictor of response to chemotherapy+ bevacizumab in patients with metastatic colorectal cancer. This is an ASCO Meeting Abstract from the 2016 ASCO Annual Meeting I.