The nucleolus—a conspicuous but obscure organelle within the cell nucleus—is normally too compact to be studied in detail. Researchers at Case Western Reserve University just learned how to simplify ...

At most, 10 people in the world are known to have BPTA. Five of them participated in the current study, and they were found to share virtually the same mutation in the gene for the HMGB1 protein. It ...

The size of a cell's nucleolus may reveal how long that cell, or even the organism it belongs to, will live. Over the past few years, researchers have been piecing together an unexpected link between ...

The secret to cellular youth may depend on keeping the nucleolus—a condensed structure inside the nucleus of a cell—small, according to Weill Cornell Medicine investigators. The findings were ...

New research has advanced understanding of how the nucleolus is assembled through a process called liquid-liquid phase separation and has identified a protein that plays key role Researchers have ...

Deep within the nucleus of every cell lies a structure smaller than a pinpoint that may hold the secret to aging. Scientists at Weill Cornell Medicine have discovered that the nucleolus, long known ...

This model of the nucleus with nucleolus (pink) shows how ribosomal DNA is correctly repaired in young cells. In old cells with enlarged nucleolus, however, DNA repair is inaccurate leading to faster ...

THE nucleolus was first figured in 1781 as a spot in the centre of a round or oval body (the nucleus) in epithelial cells of the eel. Since then it has been described in the nuclei of almost every ...