The SC3 tool was then used to analyse single-cell RNA-sequence data from two patients diagnosed with myeloproliferative neoplasm (MPN) blood cancers. Pre-malignant MPN occurs when the bone marrow ...

Single-cell sequencing provides unprecedented detail into cell-to-cell variability, uncovering key biological mechanisms in ...

An individual’s genome is identifiable. But datasets of RNA sequences from single cells are like a blurry photocopy of the genome. The sequence numbers are small, the data are noisy, and the sequences ...

Single-cell RNA-seq (scRNA-seq) has spent the past decade maturing into a foundational technology. Over that time, the technology has both laid the foundation for building cell atlases and allowed ...

Researchers have combined two sequencing technologies in single cells to find new differences in mRNAs resulting from Alzheimer's disease, dementia with Lewy bodies and Parkinson's disease. Diseases ...

It’s no secret that we need new ways to treat and detect disease, including cancer. Specifically, we need better biomarkers that can be used for diagnosis and better ways to selectively get medicine ...

All cells need to sense and respond to their environment, to know when to activate genes, build proteins, and carry out their ...

Expression of the clusterin gene in hematopoietic stem cells marks an age-related shift toward myeloid/platelet over lymphoid cell production In recent years, there has been a growing trend of an ...