Membrane fusion and budding mediate fundamental biological processes like intracellular trafficking, exocytosis, and endocytosis. For many decades, fusion has been thought to open a nanometer-range ...

CD19-targeted CAR T-cell therapy shows a 65% response rate in Richter transformation, with median progression-free survival of 8 months and overall survival of 14.4 months. Early response and age are ...

“Allogeneic transplants can be very effective, and potentially lifesaving, but not all immune cells given to a recipient are reproduced from donor cells,” said Jonathan Serody, MD. “Innate type 2 ...

New research, led by LJI scientists, offers a potential way to boost tissue-resident memory T cell numbers to better fight disease.