A new review was published in Volume 16 of Oncotarget on June 25, 2025, titled "Challenges and resistance mechanisms to EGFR targeted therapies in head and neck cancers and breast cancer: Insights ...

The field of cancer treatment saw a variety of advancements in 2025, from new dedicated centers to approved treatments to ...

Lung cancer in never-smokers exhibits distinct biological characteristics, often leading to late-stage diagnoses due to lack of screening. Targeted therapies, guided by molecular testing, offer ...

Identifying BRCAness in tumors, even in the absence of BRCA mutations, broadens the reach of targeted therapies, supporting more individualized and effective cancer treatment approaches. BRCAness ...

Recent advancements in nanotechnology have paved the way for innovative approaches in the fight against cancer. Scientists have unveiled groundbreaking cancer-fighting nanobots, promising a revolution ...

This model illustrates how SETD1B promotes the expansion of H3K4me3 epigenetic marks and upregulates MYC expression, driving cytokine-independent cell growth in FLT3-mutated AML. Acute myeloid ...

Metastatic breast cancer subtypes and biomarkers are crucial for guiding treatment decisions and managing disease progression. ER-positive, HER2-negative breast cancer treatment often begins with ...

We’ve been talking about this for years now. Personalized medicine. Or precision medicine, if you prefer that term. The idea is simple enough on paper-stop treating patients like averages and start ...

Selecting the right targeted therapy or clinical trial for each cancer patient is one of modern oncology’s greatest challenges. Each tumor carries a unique combination of four to five actionable ...

Cancer treatment resistance is one of the biggest challenges in cancer care. It occurs when cancer cells adapt to survive despite therapy, making treatments less effective or even completely ...

Not all metastatic breast cancers behave similarly in the body. Each subtype of breast cancer has distinct characteristics, which make them more likely to behave in ...