Week 17 of the 2025 NFL season kicks off with a triple-header of division rivalries on Christmas Day and wraps up Monday with the Los Angeles Rams visiting the Atlanta Falcons.

NFL Week 17 is here, so let's look at the odds and make some picks and predictions for the coming weekend as the playoffs near.

Each pick has a confidence level of 1-10, with 10 being the most confident. For more information on the pick methodology, check out the Week 1 edition of this series. Keep in mind that since the idea here is to make high-percentage plays,

The Los Angeles Rams are 9.5-point favorites against the reeling Arizona Cardinals in Week 18, according to FanDuel Sportsbook. Arizona is far and away the worst team in the NFC West and is currently on an eight-game losing streak.

Week 17 in the NFL ends with the Rams heading to Atlanta to take on the Falcons in a potentially important NFC matchup. There’s no chance to win the NFC West for Los Angeles, but if they win the next two games and the 49ers lose next week,

Expert recap and game analysis of the Cleveland Browns vs. Pittsburgh Steelers NFL game from December 28, 2025 on ESPN.

Steelers miss chance to win AFC North in defeat to Cleveland while the Patriots sealed the AFC East after thrashing the Jets and the Bills lost a nail-biter to the Eagles