Single-cell sequencing provides unprecedented detail into cell-to-cell variability, uncovering key biological mechanisms in ...

This study provides useful insights into addressing the question of whether the prevalence of autoimmune disease could be driven by sex differences in the T cell receptor (TCR) repertoire, correlating ...

Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, ...

RNA is a central biological macromolecule, now widely harnessed in medicine and nanotechnology. Like proteins, RNA function ...

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...

A study captured the first near frame-by-frame view of a self-splicing ribozyme assembling into its active form. Using ...

Industrialized, small batch, and individual RNA therapeutics become practical with “in-a-box” manufacturing technology.

Researchers have used cryo-EM and computational tools to visualize ribozyme assembly, shedding light on life's most versatile ...

We have long struggled to determine how the first living organisms on Earth came together. Now, surprising evidence hints ...

From enzymes and lipid nanoparticles to large-scale process design, four global innovators redefine RNA-based medicine development and delivery.

Human gene maps contain major blind spots because they were built largely from the DNA sequences of people with European ...

New tools that create ultra-precise maps of our tissues are transforming our ability to diagnose and cure once-fatal ...