Immunotherapy has revolutionized cancer care by training the immune system to detect and destroy tumors. For many patients, ...

This study provides useful insights into addressing the question of whether the prevalence of autoimmune disease could be driven by sex differences in the T cell receptor (TCR) repertoire, correlating ...

High-resolution structures explain the mechanism of human PNPase and provide insights into mutations causing hereditary ...

This valuable study presents an analysis of the gene regulatory networks that contribute to tumour heterogeneity and tumor plasticity in Ewing sarcoma, with key implications for other fusion-driven ...

An archaeon reads the same codon in two different ways, overturning a doctrine that has stood for 60 years. Living organisms ...

The first study to examine the extent of European ancestry biases in gene maps reveals tens of thousands of genetic ...

Researchers have used cryo-EM and computational tools to visualize ribozyme assembly, shedding light on life's most versatile ...

Single-cell sequencing provides unprecedented detail into cell-to-cell variability, uncovering key biological mechanisms in ...

The beauty of the DNA code is that organisms interpret it unambiguously. Each three-letter nucleotide sequence, or codon, in ...

We have long struggled to determine how the first living organisms on Earth came together. Now, surprising evidence hints ...

Explore the enduring challenges of treating HIV, its unique properties, and the progress made since the virus's discovery.